| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC22705.1 | folB | RO07_23580 | RO07_09940 | UDP phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| AJC23215.1 | folB | RO07_09935 | RO07_09940 | Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| AJC23215.1 | ttcA | RO07_09935 | RO07_09945 | Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA 2-thiocytidine(32) synthetase TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.721 |
| AJC23255.2 | folB | RO07_11340 | RO07_09940 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.661 |
| AJC23255.2 | folC | RO07_11340 | RO07_18275 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.431 |
| AJC23255.2 | folE | RO07_11340 | RO07_24225 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.713 |
| AJC23255.2 | folK | RO07_11340 | RO07_03455 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.660 |
| AJC23255.2 | folP | RO07_11340 | RO07_00120 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.661 |
| folB | AJC22705.1 | RO07_09940 | RO07_23580 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| folB | AJC23215.1 | RO07_09940 | RO07_09935 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| folB | AJC23255.2 | RO07_09940 | RO07_11340 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.661 |
| folB | folC | RO07_09940 | RO07_18275 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.813 |
| folB | folE | RO07_09940 | RO07_24225 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
| folB | folK | RO07_09940 | RO07_03455 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| folB | folP | RO07_09940 | RO07_00120 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.993 |
| folB | ftsH_2 | RO07_09940 | RO07_00125 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.692 |
| folB | rdgB | RO07_09940 | RO07_23855 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.661 |
| folB | ttcA | RO07_09940 | RO07_09945 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA 2-thiocytidine(32) synthetase TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.858 |
| folC | AJC23255.2 | RO07_18275 | RO07_11340 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.431 |
| folC | folB | RO07_18275 | RO07_09940 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.813 |