| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC19310.1 | AJC22873.1 | RO07_00205 | RO07_24810 | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| AJC19310.1 | ubiA | RO07_00205 | RO07_03625 | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.914 |
| AJC19310.1 | ubiC | RO07_00205 | RO07_17590 | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.916 |
| AJC22873.1 | AJC19310.1 | RO07_24810 | RO07_00205 | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| AJC22873.1 | ubiA | RO07_24810 | RO07_03625 | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.910 |
| AJC22873.1 | ubiC | RO07_24810 | RO07_17590 | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.926 |
| APD13739.1 | aroC | RO07_15365 | RO07_23515 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.976 |
| APD13739.1 | pheA | RO07_15365 | RO07_15070 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
| APD13739.1 | trpE | RO07_15365 | RO07_05775 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.923 |
| APD13739.1 | trpG | RO07_15365 | RO07_05780 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| APD13739.1 | tyrB_3 | RO07_15365 | RO07_06965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| APD13739.1 | ubiC | RO07_15365 | RO07_17590 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.879 |
| aroC | APD13739.1 | RO07_23515 | RO07_15365 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| aroC | hisC | RO07_23515 | RO07_18300 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.730 |
| aroC | pheA | RO07_23515 | RO07_15070 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.989 |
| aroC | trpE | RO07_23515 | RO07_05775 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.972 |
| aroC | trpG | RO07_23515 | RO07_05780 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.973 |
| aroC | ubiC | RO07_23515 | RO07_17590 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.816 |
| hisC | aroC | RO07_18300 | RO07_23515 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.730 |
| hisC | pheA | RO07_18300 | RO07_15070 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
