| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroB | trmJ | RO07_06675 | RO07_18385 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.433 |
| cysE_1 | trmJ | RO07_18390 | RO07_18385 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.486 |
| dus_1 | rlmE | RO07_18900 | RO07_00130 | tRNA dihydrouridine(20/20a) synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.522 |
| dus_1 | trmJ | RO07_18900 | RO07_18385 | tRNA dihydrouridine(20/20a) synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.499 |
| lptD | mltB | RO07_05165 | RO07_15140 | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.671 |
| lptD | outO_2 | RO07_05165 | RO07_05530 | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase A24 family. | 0.438 |
| lptD | rsmA | RO07_05165 | RO07_05150 | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.883 |
| lptD | trmJ | RO07_05165 | RO07_18385 | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.422 |
| mltB | lptD | RO07_15140 | RO07_05165 | Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.671 |
| mltB | rlmE | RO07_15140 | RO07_00130 | Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.464 |
| mltB | trmJ | RO07_15140 | RO07_18385 | Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.426 |
| outO_2 | lptD | RO07_05530 | RO07_05165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase A24 family. | Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.438 |
| outO_2 | trmJ | RO07_05530 | RO07_18385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase A24 family. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.400 |
| rlmE | dus_1 | RO07_00130 | RO07_18900 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | tRNA dihydrouridine(20/20a) synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.522 |
| rlmE | mltB | RO07_00130 | RO07_15140 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| rlmE | rpoZ | RO07_00130 | RO07_23835 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.696 |
| rlmE | rsmA | RO07_00130 | RO07_05150 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.738 |
| rlmE | trmJ | RO07_00130 | RO07_18385 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.591 |
| rnhB | rpoZ | RO07_19880 | RO07_23835 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.756 |
| rnhB | trmJ | RO07_19880 | RO07_18385 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.744 |