| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysE_1 | cysE_2 | RO07_18390 | RO07_21490 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
| cysE_1 | cysK | RO07_18390 | RO07_10960 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-diaminopropionate biosynthesis protein SbnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| cysE_1 | cysM | RO07_18390 | RO07_15135 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.991 |
| cysE_1 | cysS | RO07_18390 | RO07_18415 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.930 |
| cysE_1 | glyA | RO07_18390 | RO07_00900 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.833 |
| cysE_1 | hom | RO07_18390 | RO07_19585 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
| cysE_1 | ilvA | RO07_18390 | RO07_12530 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.823 |
| cysE_1 | psdht | RO07_18390 | RO07_22875 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| cysE_1 | sdaA | RO07_18390 | RO07_07670 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.916 |
| cysE_1 | serB | RO07_18390 | RO07_22895 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
| cysE_2 | cysE_1 | RO07_21490 | RO07_18390 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
| cysE_2 | cysK | RO07_21490 | RO07_10960 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-diaminopropionate biosynthesis protein SbnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
| cysE_2 | cysM | RO07_21490 | RO07_15135 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.992 |
| cysE_2 | cysS | RO07_21490 | RO07_18415 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.855 |
| cysE_2 | glyA | RO07_21490 | RO07_00900 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.833 |
| cysE_2 | hom | RO07_21490 | RO07_19585 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.862 |
| cysE_2 | ilvA | RO07_21490 | RO07_12530 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.823 |
| cysE_2 | psdht | RO07_21490 | RO07_22875 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| cysE_2 | sdaA | RO07_21490 | RO07_07670 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.916 |
| cysE_2 | serB | RO07_21490 | RO07_22895 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |