STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabD_1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (499 aa)    
Predicted Functional Partners:
acsA_1
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.925
acsA_3
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
bclA_3
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
acs
AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
gabT
4-aminobutyrate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.922
adhB_3
L-threonine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.919
flhA_1
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.918
amiE
Formamidase; Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
   
 0.911
AJC18979.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.911
Hgd_3
3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family.
  
 
 0.910
Your Current Organism:
Pandoraea sputorum
NCBI taxonomy Id: 93222
Other names: ATCC BAA-64, ATCC:BAA:64, CCUG 45026, CIP 106624, DSM 21091, LMG 18819, LMG:18819, NCTC 13161, P. sputorum, Pandoraea sputorum Coenye et al. 2000
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