STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmrR_3MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.658
marR_2
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.632
AJC18105.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.616
AJC18651.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.529
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.513
AJC17810.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.504
rpfC_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.501
AJC18373.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.479
AJC16522.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
     0.472
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.443
Your Current Organism:
Pandoraea sputorum
NCBI taxonomy Id: 93222
Other names: ATCC BAA-64, ATCC:BAA:64, CCUG 45026, CIP 106624, DSM 21091, LMG 18819, LMG:18819, NCTC 13161, P. sputorum, Pandoraea sputorum Coenye et al. 2000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.