STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cusS_1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)    
Predicted Functional Partners:
yycF_2
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.962
baeR
Two-component system response regulator BaeR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.829
arcB
Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.828
cusR
Response regulator in two-component regulatory system with CusS; regulates the copper efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.774
kdpE
Two-component system response regulator KdpE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.741
basR_2
Two-component system response regulator BasR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.731
kdpC
K+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.719
phoP
Sensor protein PhoQ; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.713
yycF_1
Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.704
barA_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.681
Your Current Organism:
Edwardsiella hoshinae
NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78
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