STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOV95614.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)    
Predicted Functional Partners:
AOV95615.1
Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.999
fdnI
Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.978
fdnH_1
Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
 
 0.973
fdhE
Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
 
 
 0.935
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
    
  0.901
kynB
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
maeB
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.815
fumB
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.811
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.805
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.804
Your Current Organism:
Edwardsiella hoshinae
NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.