STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhTMultidrug efflux pump-associated protein, AcrZ family; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (47 aa)    
Predicted Functional Partners:
acrB_2
Multidrug efflux RND transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.649
modE_1
Molybdenum-dependent transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.567
tolC
Outer membrane channel protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.542
acrB_1
Aminoglycoside/multidrug transporter subunit AcrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.400
Your Current Organism:
Edwardsiella hoshinae
NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.