node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroC | menF | A9798_05020 | A9798_05380 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.926 |
aroC | pat | A9798_05020 | A9798_14460 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminotransferase class I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
aroC | pheA | A9798_05020 | A9798_03040 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
aroC | trpE | A9798_05020 | A9798_09340 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.957 |
aroC | trpG | A9798_05020 | A9798_09345 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
aroC | tyrA | A9798_05020 | A9798_03035 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Bifunctional chorismate mutase/prephenate dehydrogenase; Catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
aroC | ubiC | A9798_05020 | A9798_15720 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. | 0.800 |
menD | menF | A9798_05385 | A9798_05380 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.997 |
menD | menH | A9798_05385 | A9798_05390 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.999 |
menF | aroC | A9798_05380 | A9798_05020 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.926 |
menF | menD | A9798_05380 | A9798_05385 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.997 |
menF | menH | A9798_05380 | A9798_05390 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.901 |
menF | pat | A9798_05380 | A9798_14460 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Aminotransferase class I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |
menF | pheA | A9798_05380 | A9798_03040 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
menF | trpE | A9798_05380 | A9798_09340 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
menF | trpG | A9798_05380 | A9798_09345 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
menF | tyrA | A9798_05380 | A9798_03035 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Bifunctional chorismate mutase/prephenate dehydrogenase; Catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
menF | tyrB | A9798_05380 | A9798_01530 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.813 |
menF | ubiC | A9798_05380 | A9798_15720 | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. | 0.910 |
menH | menD | A9798_05390 | A9798_05385 | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.999 |