STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmrHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1002 aa)    
Predicted Functional Partners:
barA_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
torS
TMAO reductase system sensor histidine kinase/response regulator TorS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.985
barA_1
Two-component sensor histidine kinase BarA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.982
cph2_2
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.972
arcB
Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.959
rcsC
Two-component system sensor histidine kinase/response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 0.919
yfgF_2
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.887
pleD
Diguanylate cyclase response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.885
yhjK
Biofilm formation regulator HmsP; HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.880
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 
 0.874
Your Current Organism:
Edwardsiella hoshinae
NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78
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