STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcrA_2Xanthine dehydrogenase molybdenum-binding subunit XdhA; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)    
Predicted Functional Partners:
ndhS
Xanthine dehydrogenase; Iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
cutM
Xanthine dehydrogenase FAD-binding subunit XdhB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
 
 0.934
ade
Adenine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.933
AOV95769.1
Molybdopterin-dependent oxidoreductase FAD-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.925
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
  0.901
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
hpt
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
deoD
Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AOV95764.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.891
Your Current Organism:
Edwardsiella hoshinae
NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78
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