STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (509 aa)    
Predicted Functional Partners:
Ahos_0311
Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
     
 0.928
Ahos_1358
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.923
Ahos_2264
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.902
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
  0.900
Ahos_0304
2-methylcitrate synthase/citrate synthase II.
     
 0.820
Ahos_2111
2-methylcitrate synthase/citrate synthase II.
     
 0.820
Ahos_1717
Formate dehydrogenase, alpha subunit.
     
  0.800
Ahos_2287
Peroxiredoxin family, PRX.
       0.651
Ahos_2063
Acetyl coenzyme A synthetase (ADP forming), alpha domain protein.
      
 0.559
Ahos_1661
Carbonic anhydrase.
    
  0.502
Your Current Organism:
Acidianus hospitalis
NCBI taxonomy Id: 933801
Other names: A. hospitalis W1, Acidianus hospitalis W1, Acidianus hospitalis str. W1, Acidianus hospitalis strain W1
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