STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0C3AC61RMI1_N domain-containing protein. (368 aa)    
Predicted Functional Partners:
A0A0C3AR54
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.997
A0A0C2X381
Uncharacterized protein.
    
 0.994
A0A0C3AVA7
ERCC4 domain-containing protein.
    
 0.972
A0A0C3AQ36
ERCC4 domain-containing protein.
    
 0.970
A0A0C3BLB1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.966
A0A0C3BNX2
Uncharacterized protein.
    
 0.966
A0A0C3BGZ5
Uncharacterized protein.
    
 0.953
M408DRAFT_5717
Uncharacterized protein.
    
 0.953
A0A0C2XME9
Uncharacterized protein.
    
 0.940
A0A0C2WR98
Uncharacterized protein.
   
 0.897
Your Current Organism:
Serendipita vermifera
NCBI taxonomy Id: 933852
Other names: S. vermifera MAFF 305830, Sebacina vermifera MAFF 305830, Serendipita vermifera MAFF 305830
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.