STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (433 aa)    
Predicted Functional Partners:
A0A0C2XI97
Uncharacterized protein.
    
 0.973
A0A0C3BHW6
DHC_N1 domain-containing protein.
    
 0.973
A0A0C2WVY3
CS domain-containing protein.
   
 0.957
A0A0C3BLD4
WD_REPEATS_REGION domain-containing protein.
   
 0.955
A0A0C3BSN8
Uncharacterized protein.
    
 
 0.953
A0A0C3BQM6
CAP-Gly domain-containing protein.
    
 0.940
A0A0C2XE28
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.916
A0A0C2X8C9
Uncharacterized protein.
   
 0.894
A0A0C3APS5
Uncharacterized protein.
    
 0.875
A0A0C3ARI8
Uncharacterized protein.
    
 0.875
Your Current Organism:
Serendipita vermifera
NCBI taxonomy Id: 933852
Other names: S. vermifera MAFF 305830, Sebacina vermifera MAFF 305830, Serendipita vermifera MAFF 305830
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.