STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK6Proprotein convertase subtilisin/kexin type 6. (796 aa)    
Predicted Functional Partners:
FREM1
FRAS1 related extracellular matrix 1.
    
 0.863
RXFP1
Relaxin family peptide receptor 1.
  
 0.822
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
  
 0.822
RXFP2
Relaxin family peptide receptor 2.
  
 0.822
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
  
 0.822
ENSCHOP00000011572
annotation not available
   
 0.744
GLA
Galactosidase alpha.
   
 0.713
BCL10
BCL10 immune signaling adaptor.
   
 0.619
MMP7
Matrix metallopeptidase 7.
    
 0.609
MMP19
Matrix metallopeptidase 19.
    
 0.609
Your Current Organism:
Choloepus hoffmanni
NCBI taxonomy Id: 9358
Other names: C. hoffmanni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.