STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1160 aa)    
Predicted Functional Partners:
PLK2
Polo like kinase 2.
    
 0.960
PLK1
Polo like kinase 1.
    
 0.960
ENSCHOP00000009717
annotation not available
    
 
 0.949
PLK4
Polo like kinase 4.
    
 0.923
TBC1D2B
TBC1 domain family member 2B.
    
 0.896
GRTP1
Growth hormone regulated TBC protein 1.
    
 0.896
ENSCHOP00000007301
annotation not available
    
 0.896
PPP2R2B
Protein phosphatase 2 regulatory subunit Bbeta.
    
 
 0.892
PPP2R2A
Protein phosphatase 2 regulatory subunit Balpha.
    
 
 0.892
CCDC174
Coiled-coil domain containing 174.
    
 
 0.775
Your Current Organism:
Choloepus hoffmanni
NCBI taxonomy Id: 9358
Other names: C. hoffmanni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.