STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF1IKAROS family zinc finger 1. (505 aa)    
Predicted Functional Partners:
CRBN
Cereblon.
    
 
 0.961
DDB1
Damage specific DNA binding protein 1.
    
 0.895
ENSCHOP00000000249
annotation not available
    
 0.854
ENSCHOP00000005565
annotation not available
    
  0.845
IKZF3
IKAROS family zinc finger 3.
   
 
0.804
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 
 0.777
ENSCHOP00000011881
annotation not available
    
 0.717
HDAC1
Histone deacetylase 1.
    
 0.714
HDAC2
Histone deacetylase 2.
    
 0.714
IKZF2
IKAROS family zinc finger 2.
   
  
0.679
Your Current Organism:
Choloepus hoffmanni
NCBI taxonomy Id: 9358
Other names: C. hoffmanni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.