GCA_000427425_00481 protein (Caldanaerobius polysaccharolyticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GCA_000427425_00481

Unannotated protein. (226 aa)

Predicted Functional Partners:

GCA_000427425_00482

0.998

GCA_000427425_00276

0.992

GCA_000427425_00478

0.969

GCA_000427425_00491

0.967

GCA_000427425_00479

0.966

GCA_000427425_00484

0.964

GCA_000427425_00494

0.953

GCA_000427425_00492

0.945

GCA_000427425_00495

0.940

GCA_000427425_00466

0.933

Your Current Organism:

Caldanaerobius polysaccharolyticus

NCBI taxonomy Id: 935948
Other names: C. polysaccharolyticus DSM 13641, Caldanaerobius polysaccharolyticus DSM 13641, Caldanaerobius polysaccharolyticus KMTHCJ, Caldanaerobius polysaccharolyticus str. DSM 13641, Caldanaerobius polysaccharolyticus strain DSM 13641, anaerobic thermophile KMTHCJ

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
GCA_000427425_00276	GCA_000427425_00466	Unannotated protein.	Unannotated protein.	0.779
GCA_000427425_00276	GCA_000427425_00478	Unannotated protein.	Unannotated protein.	0.967
GCA_000427425_00276	GCA_000427425_00479	Unannotated protein.	Unannotated protein.	0.943
GCA_000427425_00276	GCA_000427425_00481	Unannotated protein.	Unannotated protein.	0.992
GCA_000427425_00276	GCA_000427425_00484	Unannotated protein.	Unannotated protein.	0.944
GCA_000427425_00276	GCA_000427425_00491	Unannotated protein.	Unannotated protein.	0.958
GCA_000427425_00276	GCA_000427425_00492	Unannotated protein.	Unannotated protein.	0.948
GCA_000427425_00276	GCA_000427425_00494	Unannotated protein.	Unannotated protein.	0.946
GCA_000427425_00276	GCA_000427425_00495	Unannotated protein.	Unannotated protein.	0.901
GCA_000427425_00466	GCA_000427425_00276	Unannotated protein.	Unannotated protein.	0.779
GCA_000427425_00466	GCA_000427425_00478	Unannotated protein.	Unannotated protein.	0.999
GCA_000427425_00466	GCA_000427425_00479	Unannotated protein.	Unannotated protein.	0.989
GCA_000427425_00466	GCA_000427425_00481	Unannotated protein.	Unannotated protein.	0.933
GCA_000427425_00466	GCA_000427425_00482	Unannotated protein.	Unannotated protein.	0.899
GCA_000427425_00466	GCA_000427425_00484	Unannotated protein.	Unannotated protein.	0.943
GCA_000427425_00466	GCA_000427425_00491	Unannotated protein.	Unannotated protein.	0.965
GCA_000427425_00466	GCA_000427425_00492	Unannotated protein.	Unannotated protein.	0.932
GCA_000427425_00466	GCA_000427425_00494	Unannotated protein.	Unannotated protein.	0.946
GCA_000427425_00466	GCA_000427425_00495	Unannotated protein.	Unannotated protein.	0.932
GCA_000427425_00478	GCA_000427425_00276	Unannotated protein.	Unannotated protein.	0.967

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.952

expected number of edges:

24

PPI enrichment p-value:

6.1e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 89

1.42

2.51

4.44e-11

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 222

1.06

1.42

4.17e-10

GO:0043933

Protein-containing complex organization

3 of 14

1.7

1.34

0.0014

GO:1901566

Organonitrogen compound biosynthetic process

11 of 272

0.97

1.2

2.46e-09

GO:0006415

Translational termination

2 of 9

1.71

0.77

0.0304

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

8 of 46

1.61

2.86

1.66e-09

GO:0019843

rRNA binding

4 of 36

1.41

1.14

0.0018

GO:0003723

RNA binding

5 of 76

1.18

0.97

0.0017

GO:0003676

Nucleic acid binding

6 of 261

0.73

0.43

0.0328

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

8 of 50

1.57

2.83

6.05e-10

GO:0044391

Ribosomal subunit

4 of 13

1.85

2.36

5.57e-06

GO:0015935

Small ribosomal subunit

2 of 6

1.89

1.18

0.0047

GO:0015934

Large ribosomal subunit

2 of 7

1.82

1.14

0.0054

GO:0005622

Intracellular anatomical structure

11 of 643

0.6

0.55

4.33e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:133

Ribosome, and Translation regulator activity

10 of 77

1.48

2.86

2.36e-12

CL:146

Structural constituent of ribosome

7 of 45

1.56

2.55

1.44e-08

CL:137

Ribosome, and Translation regulator activity

8 of 66

1.45

2.38

3.08e-09

CL:127

Translation, and Protein export

11 of 117

1.34

2.37

1.74e-12

CL:147

Structural constituent of ribosome

6 of 38

1.56

2.3

3.04e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 50

1.57

2.83

6.65e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

4 of 35

1.42

1.29

0.00059

GOCC:0043229

Intracellular organelle

8 of 179

1.02

1.06

1.60e-05

GOCC:0043232

Intracellular non-membrane-bounded organelle

5 of 91

1.1

0.96

0.00086

GOCC:0005622

Intracellular

11 of 639

0.6

0.54

2.23e-05

GOCC:0110165

Cellular anatomical entity

11 of 1266

0.3

0.26

0.0112

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

8 of 51

1.56

2.74

1.50e-09

KW-0699

rRNA-binding

4 of 34

1.44

1.26

0.00082

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