node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CVT25_002158 | CVT25_005440 | A0A409X0A5 | A0A409XC84 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ERCC4 domain-containing protein. | 0.959 |
CVT25_002158 | CVT25_005854 | A0A409X0A5 | A0A409VLY6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.656 |
CVT25_002158 | CVT25_012685 | A0A409X0A5 | A0A409VN42 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | NTF2 domain-containing protein. | 0.898 |
CVT25_002158 | CVT25_013974 | A0A409X0A5 | A0A409XPL4 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | MPN domain-containing protein. | 0.878 |
CVT25_002158 | CVT25_014973 | A0A409X0A5 | A0A409XI63 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.936 |
CVT25_002158 | CVT25_015232 | A0A409X0A5 | A0A409XRA2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Ig-like domain-containing protein. | 0.965 |
CVT25_002158 | CVT25_015247 | A0A409X0A5 | A0A409XR17 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.966 |
CVT25_003293 | CVT25_005440 | A0A409WMI6 | A0A409XC84 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | ERCC4 domain-containing protein. | 0.962 |
CVT25_003293 | CVT25_005854 | A0A409WMI6 | A0A409VLY6 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Uncharacterized protein. | 0.802 |
CVT25_003293 | CVT25_008582 | A0A409WMI6 | A0A409XNG8 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.902 |
CVT25_003293 | CVT25_012685 | A0A409WMI6 | A0A409VN42 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | NTF2 domain-containing protein. | 0.969 |
CVT25_003293 | CVT25_013974 | A0A409WMI6 | A0A409XPL4 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | MPN domain-containing protein. | 0.960 |
CVT25_003293 | CVT25_014973 | A0A409WMI6 | A0A409XI63 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Uncharacterized protein. | 0.944 |
CVT25_003293 | CVT25_015232 | A0A409WMI6 | A0A409XRA2 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Ig-like domain-containing protein. | 0.661 |
CVT25_003293 | CVT25_015247 | A0A409WMI6 | A0A409XR17 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.661 |
CVT25_005440 | CVT25_002158 | A0A409XC84 | A0A409X0A5 | ERCC4 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.959 |
CVT25_005440 | CVT25_003293 | A0A409XC84 | A0A409WMI6 | ERCC4 domain-containing protein. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.962 |
CVT25_005440 | CVT25_005854 | A0A409XC84 | A0A409VLY6 | ERCC4 domain-containing protein. | Uncharacterized protein. | 0.998 |
CVT25_005440 | CVT25_008582 | A0A409XC84 | A0A409XNG8 | ERCC4 domain-containing protein. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.792 |
CVT25_005440 | CVT25_012685 | A0A409XC84 | A0A409VN42 | ERCC4 domain-containing protein. | NTF2 domain-containing protein. | 0.961 |