STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT25_004220Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)    
Predicted Functional Partners:
CVT25_003409
FH2 domain-containing protein.
    
 0.959
CVT25_001932
Uncharacterized protein; Belongs to the actin family.
    
 0.944
CVT25_012401
Uncharacterized protein; Belongs to the actin family.
    
 0.944
CVT25_007350
Uncharacterized protein.
    
 0.944
CVT25_015316
DUF1708 domain-containing protein.
    
 0.932
CVT25_012802
DUF1708 domain-containing protein.
    
 0.932
CVT25_007016
Uncharacterized protein; Belongs to the actin family.
   
 0.928
CVT25_009036
CAP_N domain-containing protein.
   
 0.924
CVT25_011400
C-CAP/cofactor C-like domain-containing protein.
   
 0.924
CVT25_002974
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.918
Your Current Organism:
Psilocybe cyanescens
NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.