STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT25_013972TPR_REGION domain-containing protein. (344 aa)    
Predicted Functional Partners:
CVT25_010136
Uncharacterized protein.
    
 0.952
CVT25_000565
Uncharacterized protein.
   
 0.935
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
   
 0.905
CVT25_015033
Uncharacterized protein.
   
 0.894
CVT25_012498
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.858
CVT25_000432
CDC73_C domain-containing protein.
    
 0.850
CVT25_013954
TPR_REGION domain-containing protein.
    
 0.848
CVT25_001749
Uncharacterized protein.
   
 0.846
CVT25_010156
Uncharacterized protein.
    
 0.846
CVT25_000276
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.846
Your Current Organism:
Psilocybe cyanescens
NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.