STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8PIJ3_SERL3Uncharacterized protein. (530 aa)    
Predicted Functional Partners:
F8QBU1_SERL3
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.914
F8PMT5_SERL3
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
     
 0.892
F8Q0R5_SERL3
Uncharacterized protein.
   
 
 0.875
F8PUI7_SERL3
SET domain-containing protein.
     
 0.870
F8QFY9_SERL3
WD_REPEATS_REGION domain-containing protein.
    
 0.800
F8PQ39_SERL3
WD_REPEATS_REGION domain-containing protein.
    
 0.798
F8Q7C1_SERL3
B30.2/SPRY domain-containing protein.
    
 0.798
F8QEU6_SERL3
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.793
F8Q9G6_SERL3
Uncharacterized protein.
    
 0.791
F8PTV0_SERL3
Uncharacterized protein.
    
 0.782
Your Current Organism:
Serpula lacrymans
NCBI taxonomy Id: 936435
Other names: S. lacrymans var. lacrymans S7.3, Serpula lacrymans var. lacrymans S7.3
Server load: low (28%) [HD]