STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8PJB6_SERL3WD_REPEATS_REGION domain-containing protein. (604 aa)    
Predicted Functional Partners:
F8PYF1_SERL3
Uncharacterized protein; Belongs to the actin family.
   
 0.949
F8PEX0_SERL3
Uncharacterized protein.
   
 0.929
F8PHK4_SERL3
Uncharacterized protein; Belongs to the actin family.
   
 0.929
F8PY99_SERL3
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.920
F8PZZ7_SERL3
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.905
F8Q463_SERL3
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.890
F8PZ99_SERL3
Uncharacterized protein.
   
 0.869
F8PZA0_SERL3
Uncharacterized protein; Belongs to the actin family.
   
 0.869
F8Q4T3_SERL3
Uncharacterized protein; Belongs to the actin family.
   
 0.869
F8QFB2_SERL3
Uncharacterized protein.
   
 0.869
Your Current Organism:
Serpula lacrymans
NCBI taxonomy Id: 936435
Other names: S. lacrymans var. lacrymans S7.3, Serpula lacrymans var. lacrymans S7.3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.