STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8PUA7_SERL3Uncharacterized protein. (679 aa)    
Predicted Functional Partners:
F8PQB6_SERL3
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.980
F8QFI9_SERL3
Protein kinase domain-containing protein.
  
0.980
F8Q3P6_SERL3
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.966
F8QEL3_SERL3
Uncharacterized protein.
    
 0.964
F8Q7D0_SERL3
Rhodanese domain-containing protein.
   
 0.961
F8PQP0_SERL3
MRC1 domain-containing protein.
    
 0.957
F8PP18_SERL3
RFX-type winged-helix domain-containing protein.
   
 0.951
F8PL54_SERL3
Serine/threonine-protein kinase.
  
0.938
F8PW00_SERL3
Protein kinase domain-containing protein.
  
 
 0.928
F8PQT7_SERL3
Protein kinase domain-containing protein.
    
 
0.908
Your Current Organism:
Serpula lacrymans
NCBI taxonomy Id: 936435
Other names: S. lacrymans var. lacrymans S7.3, Serpula lacrymans var. lacrymans S7.3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.