STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8QEM3_SERL3Uncharacterized protein. (311 aa)    
Predicted Functional Partners:
F8Q0S4_SERL3
Uncharacterized protein.
   
 0.996
F8PYN8_SERL3
RRM domain-containing protein.
   
 
 0.989
F8PKX6_SERL3
Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.
    
 
 0.978
F8PMF2_SERL3
Uncharacterized protein.
   
 0.977
F8QF75_SERL3
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
    
 0.975
F8Q728_SERL3
Nuclear cap-binding protein subunit 2.
    
 
 0.971
F8PWR4_SERL3
Uncharacterized protein.
    
 0.961
F8PV64_SERL3
CPSF_A domain-containing protein.
    
 0.955
F8QHM6_SERL3
Sm domain-containing protein.
    
 0.955
F8PGG6_SERL3
Small nuclear ribonucleoprotein Sm D2.
   
 
 0.948
Your Current Organism:
Serpula lacrymans
NCBI taxonomy Id: 936435
Other names: S. lacrymans var. lacrymans S7.3, Serpula lacrymans var. lacrymans S7.3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.