STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCHFRGTP cyclohydrolase 1 feedback regulatory protein. (84 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1 isoform X1.
    
 0.993
DNAJC12
dnaJ homolog subfamily C member 12 isoform X2.
      
 0.771
STUB1
E3 ubiquitin-protein ligase CHIP.
      
 0.703
ENSEEUP00000000413
annotation not available
     
 0.686
PTS
6-pyruvoyl tetrahydrobiopterin synthase.
     
 0.686
SPR
Sepiapterin reductase.
      
 0.531
XDH
Xanthine dehydrogenase.
      
 0.504
ADRA1B
alpha-1B adrenergic receptor.
      
 0.495
HTR1A
5-hydroxytryptamine receptor 1A.
      
 0.489
BCO1
Beta,beta-carotene 15,15'-dioxygenase isoform X1.
      
 0.469
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.