node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APEX1 | APEX2 | ENSEEUP00000011435 | ENSEEUP00000012002 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.890 |
APEX1 | MUTYH | ENSEEUP00000011435 | ENSEEUP00000014028 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.890 |
APEX1 | NEIL1 | ENSEEUP00000011435 | ENSEEUP00000013260 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Endonuclease 8-like 1. | 0.485 |
APEX1 | NEIL2 | ENSEEUP00000011435 | ENSEEUP00000011468 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Endonuclease 8-like 2. | 0.487 |
APEX1 | NEIL3 | ENSEEUP00000011435 | ENSEEUP00000009878 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Endonuclease 8-like 3. | 0.449 |
APEX1 | OGG1 | ENSEEUP00000011435 | ENSEEUP00000000198 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | N-glycosylase/DNA lyase. | 0.884 |
APEX1 | XRCC1 | ENSEEUP00000011435 | ENSEEUP00000013616 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA repair protein XRCC1 isoform X2. | 0.718 |
APEX2 | APEX1 | ENSEEUP00000012002 | ENSEEUP00000011435 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.890 |
APEX2 | MUTYH | ENSEEUP00000012002 | ENSEEUP00000014028 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.875 |
APEX2 | OGG1 | ENSEEUP00000012002 | ENSEEUP00000000198 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | N-glycosylase/DNA lyase. | 0.836 |
APEX2 | XRCC1 | ENSEEUP00000012002 | ENSEEUP00000013616 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA repair protein XRCC1 isoform X2. | 0.479 |
ENSEEUP00000000193 | OGG1 | ENSEEUP00000000193 | ENSEEUP00000000198 | annotation not available | N-glycosylase/DNA lyase. | 0.811 |
ENSEEUP00000000193 | PNP | ENSEEUP00000000193 | ENSEEUP00000002195 | annotation not available | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.517 |
MUTYH | APEX1 | ENSEEUP00000014028 | ENSEEUP00000011435 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.890 |
MUTYH | APEX2 | ENSEEUP00000014028 | ENSEEUP00000012002 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.875 |
MUTYH | NEIL1 | ENSEEUP00000014028 | ENSEEUP00000013260 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease 8-like 1. | 0.636 |
MUTYH | NEIL2 | ENSEEUP00000014028 | ENSEEUP00000011468 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease 8-like 2. | 0.709 |
MUTYH | NEIL3 | ENSEEUP00000014028 | ENSEEUP00000009878 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease 8-like 3. | 0.744 |
MUTYH | OGG1 | ENSEEUP00000014028 | ENSEEUP00000000198 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | N-glycosylase/DNA lyase. | 0.986 |
MUTYH | SNRPB | ENSEEUP00000014028 | ENSEEUP00000014212 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). | 0.776 |