STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa)    
Predicted Functional Partners:
PYCR3
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
0.945
LOC103122770
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.941
ALDH4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X2; Belongs to the aldehyde dehydrogenase family.
  
 0.918
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.870
P4HA2
Prolyl 4-hydroxylase subunit alpha-2 isoform X1.
     
 0.867
LAP3
Cytosol aminopeptidase.
    
  0.865
P4HA3
Prolyl 4-hydroxylase subunit alpha-3.
     
 0.863
L3HYPDH
trans-3-hydroxy-L-proline dehydratase.
    
 0.788
GOT1
Aspartate aminotransferase.
    
 0.785
MYADML2
Myeloid-associated differentiation marker-like protein 2.
 
   
  0.742
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.