STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKPleckstrin. (350 aa)    
Predicted Functional Partners:
ENSEEUP00000004934
annotation not available
      
 0.774
BIN1
Myc box-dependent-interacting protein 1 isoform X4.
   
  
 0.753
ENSEEUP00000007134
annotation not available
   
 
 0.704
CDC42
Cell division control protein 42 homolog isoform X1.
   
 
 0.704
SRC
Tyrosine-protein kinase.
   
  
 0.700
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
  
 0.663
CNN3
Calponin 3.
     
 0.660
BTK
Tyrosine-protein kinase.
   
  
 0.645
ENSEEUP00000002561
annotation not available
      
 0.644
RABIF
Guanine nucleotide exchange factor MSS4.
      
 0.644
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.