STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGO4Argonaute RISC component 4. (861 aa)    
Predicted Functional Partners:
ENSEEUP00000007832
annotation not available
  
 
0.961
ENSEEUP00000003596
annotation not available
   
 0.954
TNRC6C
Trinucleotide repeat-containing gene 6C protein isoform X2.
    
 0.930
TNRC6A
Trinucleotide repeat-containing gene 6A protein isoform X1.
    
 0.871
DROSHA
Ribonuclease 3.
    
 0.824
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.800
ENSEEUP00000001573
annotation not available
    
 0.800
PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1.
    
 0.788
STAU2
Double-stranded RNA-binding protein Staufen homolog 2-like.
    
 0.785
MRPL44
39S ribosomal protein L44, mitochondrial.
    
 0.784
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.