STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C11orf54Ester hydrolase C11orf54 homolog isoform X1. (219 aa)    
Predicted Functional Partners:
ENSEEUP00000000657
annotation not available
 
    
 0.804
MED17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
 
    
 0.643
TBC1D22B
TBC1 domain family member 22B.
      
 0.641
CCDC82
Coiled-coil domain-containing protein 82.
      
 0.632
NARS1
asparagine--tRNA ligase, cytoplasmic isoform X1.
      
 0.530
PDE4DIP
Myomegalin-like.
      
 0.504
HDLBP
Vigilin.
      
 0.501
LIPH
Lipase member H.
      
 0.499
SGO2
LOW QUALITY PROTEIN: shugoshin-like 2.
      
 0.497
ENSEEUP00000008508
annotation not available
      
 0.495
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.