STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARFGAP1ADP-ribosylation factor GTPase-activating protein 1 isoform X2. (417 aa)    
Predicted Functional Partners:
ARFGAP2
ADP-ribosylation factor GTPase-activating protein 2 isoform X3.
   
 0.930
ARFGAP3
ADP-ribosylation factor GTPase-activating protein 3.
   
0.930
GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X2.
    
 0.896
ENSEEUP00000008668
annotation not available
   
 0.854
COPB2
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.850
ARF1
ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
   
 0.844
ARL6
ADP-ribosylation factor-like protein 6; Belongs to the small GTPase superfamily. Arf family.
   
 0.844
SMAP2
Stromal membrane-associated protein 2 isoform X1.
    
0.835
SMAP1
Stromal membrane-associated protein 1 isoform X1.
    
 0.835
ARL5B
Putative ADP-ribosylation factor-like protein 5C; Belongs to the small GTPase superfamily. Arf family.
   
 0.825
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.