STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMENeprilysin. (750 aa)    
Predicted Functional Partners:
DPP4
Dipeptidyl peptidase 4.
     
 0.932
ACE2
Angiotensin-converting enzyme.
     
 0.929
CLTRN
Collectrin.
     
 0.929
PRCP
Lysosomal Pro-X carboxypeptidase.
     
 0.928
MEP1A
Meprin A subunit.
     
 0.881
MEP1B
Metalloendopeptidase.
     
 0.877
ENSEEUP00000006374
annotation not available
    
 0.875
XPNPEP2
xaa-Pro aminopeptidase 2; Belongs to the peptidase M24B family.
   
 
 0.874
RDX
Radixin isoform X1.
    
 
 0.837
ENSEEUP00000002020
annotation not available
      
 0.834
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.