STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog. (1033 aa)    
Predicted Functional Partners:
PPP2R2B
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 0.907
ZCCHC2
Zinc finger CCHC domain-containing protein 2.
    
 
 0.835
PPME1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
    
 0.830
ENSEEUP00000001610
annotation not available
   
 0.816
PPP2CB
Serine/threonine-protein phosphatase.
   
 0.816
PPP4C
Serine/threonine-protein phosphatase.
    
 0.773
SGO1
Shugoshin-like 1.
    
 0.761
PPP2R5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
   
 0.757
PPP2R5C
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
   
 0.757
PPP2R5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
   
 0.757
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.