node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AADAT | ACMSD | ENSEEUP00000005634 | ENSEEUP00000004127 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | 0.553 |
AADAT | AFMID | ENSEEUP00000005634 | ENSEEUP00000002163 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.942 |
AADAT | ENSEEUP00000001687 | ENSEEUP00000005634 | ENSEEUP00000001687 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | annotation not available | 0.935 |
AADAT | ENSEEUP00000003296 | ENSEEUP00000005634 | ENSEEUP00000003296 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | annotation not available | 0.920 |
AADAT | HAAO | ENSEEUP00000005634 | ENSEEUP00000003944 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | 3-hydroxyanthranilate 3,4-dioxygenase. | 0.536 |
AADAT | KYAT3 | ENSEEUP00000005634 | ENSEEUP00000000540 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | Kynurenine aminotransferase 3. | 0.936 |
AADAT | KYNU | ENSEEUP00000005634 | ENSEEUP00000001886 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.918 |
ACMSD | AADAT | ENSEEUP00000004127 | ENSEEUP00000005634 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | 0.553 |
ACMSD | AFMID | ENSEEUP00000004127 | ENSEEUP00000002163 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.751 |
ACMSD | ENSEEUP00000001687 | ENSEEUP00000004127 | ENSEEUP00000001687 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | annotation not available | 0.835 |
ACMSD | ENSEEUP00000003296 | ENSEEUP00000004127 | ENSEEUP00000003296 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | annotation not available | 0.648 |
ACMSD | HAAO | ENSEEUP00000004127 | ENSEEUP00000003944 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | 3-hydroxyanthranilate 3,4-dioxygenase. | 0.968 |
ACMSD | KYAT3 | ENSEEUP00000004127 | ENSEEUP00000000540 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | Kynurenine aminotransferase 3. | 0.587 |
ACMSD | KYNU | ENSEEUP00000004127 | ENSEEUP00000001886 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.891 |
AFMID | AADAT | ENSEEUP00000002163 | ENSEEUP00000005634 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1. | 0.942 |
AFMID | ACMSD | ENSEEUP00000002163 | ENSEEUP00000004127 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | 0.751 |
AFMID | ENSEEUP00000001687 | ENSEEUP00000002163 | ENSEEUP00000001687 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | annotation not available | 0.949 |
AFMID | ENSEEUP00000003296 | ENSEEUP00000002163 | ENSEEUP00000003296 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | annotation not available | 0.965 |
AFMID | HAAO | ENSEEUP00000002163 | ENSEEUP00000003944 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 3-hydroxyanthranilate 3,4-dioxygenase. | 0.547 |
AFMID | KYAT3 | ENSEEUP00000002163 | ENSEEUP00000000540 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynurenine aminotransferase 3. | 0.967 |