STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIGMAR1Sigma non-opioid intracellular receptor 1 isoform X1. (223 aa)    
Predicted Functional Partners:
FAXDC2
Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family.
   
 0.977
MSMO1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.977
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 0.969
CYP51A1
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
   
 
 0.962
ENSEEUP00000001258
annotation not available
   
 
 0.961
ERG28
Probable ergosterol biosynthetic protein 28.
   
 
 0.957
LBR
lamin-B receptor.
   
 
 0.930
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.930
SDR42E1
Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family.
   
 
 0.880
HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7; Belongs to the 3-beta-HSD family.
   
 
 0.880
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.