STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (183 aa)    
Predicted Functional Partners:
STARD3NL
MLN64 N-terminal domain homolog.
 
   
 0.940
VDAC1
Voltage dependent anion channel 1.
     
 0.924
VDAC2
Voltage-dependent anion-selective channel protein 2.
     
 0.882
VDAC3
Voltage-dependent anion-selective channel protein 3 isoform X2.
     
 0.882
HSD17B3
Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.864
LOC103124327
Cytochrome P450 11B1, mitochondrial-like; Belongs to the cytochrome P450 family.
   
 
 0.840
MC2R
Adrenocorticotropic hormone receptor.
      
 0.818
ENSEEUP00000008267
annotation not available
   
 
 0.810
FSHR
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
   
  
 0.787
FDX1
Adrenodoxin, mitochondrial.
   
 
 0.773
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.