STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT2ARF GTPase-activating protein GIT2 isoform X1. (740 aa)    
Predicted Functional Partners:
PXN
Paxillin.
    
 0.978
ARHGEF6
Rho guanine nucleotide exchange factor 6 isoform X2.
    
 0.967
ENSEEUP00000007134
annotation not available
    
 0.928
CDC42
Cell division control protein 42 homolog isoform X1.
    
 0.928
GIT1
ARF GTPase-activating protein GIT1 isoform X1.
  
 
0.916
ENSEEUP00000010018
annotation not available
   
 
 0.896
ENSEEUP00000006064
annotation not available
    
 0.880
SRC
Tyrosine-protein kinase.
     
 0.878
ENSEEUP00000013071
annotation not available
    
 0.821
WASF1
wiskott-Aldrich syndrome protein family member 1 isoform X1.
     
 0.811
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.