STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1041 aa)    
Predicted Functional Partners:
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.998
ENSEEUP00000007667
annotation not available
   
 0.998
PXN
Paxillin.
    
 0.982
VCAM1
Vascular cell adhesion protein 1.
   
 0.971
ENSEEUP00000005695
annotation not available
   
 0.962
FN1
Fibronectin isoform X2.
    
 0.956
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.954
ITGB4
Integrin beta.
   
 0.954
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.950
ITGA5
Integrin alpha-5; Belongs to the integrin alpha chain family.
    
0.946
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.