STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INSCProtein inscuteable homolog isoform X1. (570 aa)    
Predicted Functional Partners:
ENSEEUP00000009516
annotation not available
    
 
 0.925
TLN1
Talin-1 isoform X2.
    
 0.794
ENSEEUP00000006256
annotation not available
    
 0.794
PI4KB
Phosphatidylinositol 4-kinase beta isoform X6; Belongs to the PI3/PI4-kinase family.
   
 0.697
LOC107523109
Uncharacterized protein LOC107523109.
   
 0.695
SEC61G
Protein transport protein Sec61 subunit gamma.
   
 
 0.677
INPPL1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2.
     
 0.672
SACM1L
Phosphatidylinositide phosphatase SAC1 isoform X1.
    
 0.664
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.643
ENSEEUP00000005463
annotation not available
      
 0.636
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.