STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APBB2Amyloid beta A4 precursor protein-binding family B member 2 isoform X1. (640 aa)    
Predicted Functional Partners:
APP
Amyloid beta A4 protein isoform X1.
    
 0.955
ENSEEUP00000008971
annotation not available
    
 0.955
APLP1
Amyloid-like protein 1 isoform X1.
    
 0.793
ENSEEUP00000002291
annotation not available
    
 0.754
ENSEEUP00000008436
annotation not available
    
 0.754
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
  0.725
KAT8
Lysine acetyltransferase 8.
    
 0.724
KAT7
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.724
ENSEEUP00000011699
annotation not available
    
 0.724
MAPK8
Mitogen-activated protein kinase.
    
 0.721
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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