STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BLVRABiliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. (296 aa)    
Predicted Functional Partners:
HMOX1
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
     
 0.957
BLVRB
Flavin reductase (NADPH).
   
 
 0.955
ENSEEUP00000007119
annotation not available
     
 0.935
UGT2A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.867
ENSEEUP00000001429
annotation not available
  
 
 0.806
TGDS
dTDP-D-glucose 4,6-dehydratase.
  
 
 0.762
KARS1
Lysine--tRNA ligase.
  
    0.738
SORD
Sorbitol dehydrogenase.
  
 
 0.733
GALK2
N-acetylgalactosamine kinase isoform X1.
  
 0.714
ENSEEUP00000014311
annotation not available
  
 0.714
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.