STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCLNucleolin isoform X2. (705 aa)    
Predicted Functional Partners:
HNRNPU
Heterogeneous nuclear ribonucleoprotein U.
   
 
 0.908
EIF3A
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]
   
 
 0.889
HNRNPA2B1
Heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1.
  
0.878
NCBP2L
Nuclear cap binding protein subunit 2 like.
   
 0.853
NOP56
Nucleolar protein 56.
   
 0.832
NCBP1
Nuclear cap-binding protein subunit 1.
    
 0.823
EIF4E1B
Eukaryotic translation initiation factor 4E type 1B-like; Belongs to the eukaryotic initiation factor 4E family.
   
 0.816
EIF4E3
Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family.
    
 0.813
SERBP1
Plasminogen activator inhibitor 1 RNA-binding protein isoform X1.
   
 
 0.812
EIF4A3
Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.
   
 0.808
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.