STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMX1ALIM homeobox transcription factor 1-alpha. (383 aa)    
Predicted Functional Partners:
LDB1
LIM domain-binding protein 1 isoform X2.
    
 0.755
LDB2
LIM domain binding 2.
    
 0.745
OTX2
Orthodenticle homeobox 2.
    
 
 0.701
OTX2-2
Homeobox protein OTX2 isoform X1.
    
 
 0.701
PAX2
LOW QUALITY PROTEIN: paired box protein Pax-2.
    
 
 0.639
PAX5
Paired box protein Pax-5 isoform X1.
    
 
 0.639
TLX3
T-cell leukemia homeobox protein 3.
    
 
 0.616
ENSEEUP00000013043
annotation not available
    
 
 0.615
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 
 0.576
GATA3
Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.
    
 0.571
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.