STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC45Cell division control protein 45 homolog. (481 aa)    
Predicted Functional Partners:
MCM6
DNA helicase; Belongs to the MCM family.
   
 0.999
MCM3
DNA helicase; Belongs to the MCM family.
   
 0.999
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
 0.999
MCM7
Minichromosome maintenance complex component 7.
   
 0.999
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.999
MCM2
DNA helicase; Belongs to the MCM family.
   
 0.999
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 0.997
ENSEEUP00000013883
annotation not available
   
 0.996
GINS4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 0.995
POLE2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.995
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.