STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAB1GRB2-associated-binding protein 1. (648 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.998
ENSEEUP00000008074
annotation not available
    
 0.996
MET
Hepatocyte growth factor receptor.
    
 0.987
EGFR
Receptor protein-tyrosine kinase.
   
 0.986
MST1R
Macrophage-stimulating protein receptor.
    
 0.985
ENSEEUP00000007255
annotation not available
    
 0.981
SOS1
Son of sevenless homolog 1 isoform X1.
    
 0.975
CRK
Adapter molecule crk isoform X1.
    
 0.973
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.964
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.948
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.