STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LUZP1Leucine zipper protein 1. (1073 aa)    
Predicted Functional Partners:
DAPK2
Death-associated protein kinase 2.
    
 
 0.877
DAPK1
Death-associated protein kinase 1.
    
 
 0.702
CCSER2
Serine-rich coiled-coil domain-containing protein 2 isoform X2.
      
 0.619
NOC2L
Nucleolar complex protein 2 homolog.
      
 0.603
LRRC47
Leucine-rich repeat-containing protein 47.
      
 0.532
FAM117B
Protein FAM117B.
      
 0.532
KIDINS220
Kinase D-interacting substrate of 220 kDa isoform X6.
    
 
 0.502
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
      
 0.497
DNAJC16
DnaJ heat shock protein family (Hsp40) member C16.
      
 0.495
CCNL1
cyclin-L1 isoform X1; Belongs to the cyclin family.
      
 0.495
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.