STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAP1Ubiquitin carboxyl-terminal hydrolase. (576 aa)    
Predicted Functional Partners:
ASXL2
Putative Polycomb group protein ASXL2.
    
 0.990
BARD1
BRCA1-associated RING domain protein 1.
    
 0.976
HCFC1
Host cell factor 1.
    
 0.968
ENSEEUP00000011809
annotation not available
    
 0.968
ADRM1
Proteasomal ubiquitin receptor ADRM1.
   
 0.967
PSMD4
26S proteasome non-ATPase regulatory subunit 4 isoform X1.
    
 0.966
ASXL1
Putative Polycomb group protein ASXL1.
    
 0.965
ASXL3
Putative Polycomb group protein ASXL3.
    
 0.952
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.947
ENSEEUP00000005899
annotation not available
   
 0.946
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.