STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (498 aa)    
Predicted Functional Partners:
TREM2
Triggering receptor expressed on myeloid cells 2 isoform X2.
    
 
 0.802
APP
Amyloid beta A4 protein isoform X1.
   
 0.778
ENSEEUP00000008971
annotation not available
   
 0.778
ENSEEUP00000014440
annotation not available
   
 0.716
C7
Complement component C7.
   
 0.713
ENSEEUP00000005051
annotation not available
    
 
 0.703
ENSEEUP00000010966
annotation not available
   
 0.700
ENSEEUP00000005697
annotation not available
   
 0.692
CD59
CD59 glycoprotein.
      
 0.664
ENSEEUP00000000298
annotation not available
   
 0.655
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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